Article Critique

ARTICLE CRITIQUE 2

ArticleCritique

NameInstitutionalAffiliation

Bennett,W., Maruthur, N., Singh, S., Segal, J., Wilson, L., &amp Chatterjee,R. et al. (2011). Comparative Effectiveness and Safety of Medicationsfor Type 2 Diabetes: An Update Including New Drugs and 2-DrugCombinations.&nbspAnnalsof Internal Medicine,&nbsp154(9),602. http://dx.doi.org/10.7326/0003-4819-154-9-201105030-00336

Thepurpose of this study was to compare the effectiveness and safety ofvarious oral medications used in the treatment of type 2 diabetes.The researchers utilized a systematic review approach where theysearched through various databases for observational studies andtrials on type 2 diabetes medication. Their focus was on the possiblebenefits and harms of various drugs including second generationsulfonylureas,meglitinides, metformin and thiazolidinediones. The databases thatthe researchers utilized in this study were EMBASE, MEDLINE as wellas the Cochrane Central Register of Controlled Trials.

Bennetet al. (2011) point out that there has been an increase in the rangeof medication available for treatment of type 2 diabetes. They are ofthe view that due to availability of many different drugs, it isimportant for both the patients and medical practitioners to knowabout the safety and effectiveness of these medications in order tomake choices that are informed. This statement justifies the reasonfor conducting the study. Two independent researchers did the processof study selection and data extraction. A total of 26 observationalstudies and 140 trial studies were identified. These studiespresented a head-to-head comparison of different type 2 diabetestreatment regimes. Bennet et al. (2011) reports that metformin is themost effective first line agent for type 2 diabetes treatment.Additionally, it is reported that reduced hemoglobin levels are oftenachieved with most 2-drug combinations, but such combinations lead toincreased risk for hypoglycemia and other events of adverse nature.

Thetwo independent researchers were able to identify the appropriatestudies through reviewing of the titles and abstract. However, Ibelieve that reviewing of titles and abstracts alone was not the mostappropriate approach since the searches could bring up unrelatedstudies. The researchers report that they made a qualitative andquantitative synthesis of the outcomes. Through utilization of boththe qualitative and quantitative approaches, the study ensured thatrigor and validity were upheld.

Ingeneral, the articles title is clear and appropriate as it states themain purpose of the study and the area of focus. Additionally, thearticle is well organized, with headings and subheadings, which makesit easier for readers to switch from one section of the article toanother. The researchers make good use of numerous scholarly articlesto support their arguments. However, some of the articles used areoutdated. It would be better for the researchers to delete some ofthese articles from their references, especially those publishedbefore the year 2000. However, the discussion presented by theauthors is relevant and the article is objective in the discussion ofeffectiveness and safety of the different type 2 diabetes medication.

Thestudy is not conclusive since it made use of only three databases.Additionally, the researchers made use of only those articlespublished in English, meaning that there is a possibility they missedimportant information on type 2 diabetes treatment published in otherlanguages. Despite this shortcoming, the authors were able to presentthe procedures in enough detail. The details provided for theprocedures are enough for readers to duplicate them in similarstudies.

References

Bennett,W., Maruthur, N., Singh, S., Segal, J., Wilson, L., &amp Chatterjee,R. et al. (2011). Comparative Effectiveness and Safety of Medicationsfor Type 2 Diabetes: An Update Including New Drugs and 2-DrugCombinations.&nbspAnnalsof Internal Medicine,&nbsp154(9),602. http://dx.doi.org/10.7326/0003-4819-154-9-201105030-00336