is the science behind drug distribution in the body and it majorlyfocuses on the changes that the body experiences in the concentrationof drug plasma. For every drug or dose, the level of the medicationwill rise and fall depending upon the rate of the process ofabsorption, distribution and elimination. Numerous factors affect thepharmacokinetics process, and these are food and other drugs (Acharya& Shrivastava, 2008). These two components have a significanteffect on both extent and the rate of the pharmaceutical medicationespecially consuming it orally. It is the understanding of food andany other administered medications that enable professionals to beable to advise patients about taking drugs with or without food.
Theunderstanding of the clinical side effects consuming medications on afull or empty stomach is crucial if one want to achieve the qualityuse of medicine. Despite the fact that the impact of food and drug isnot clinical Important for some drugs, there are interactions betweenfood and medications that may have adverse consequences. In mostcases, these interactions can be avoided by advising the patient themedicines with respect to meals.
Mealsand other medication may either slow down or increase the total rateof medicine absorption. The constituents of food consumed are used toinfluence chances of experiencing gastric emptying issues. It isimportant to note that any delay especially of the administeredmedication reaching the human small intestines can easily lead to adelay of its respective into the most sensitive human circulatorysystem. As a result of this absorption, it is important to have anoral administration of medicines under conditions that are fast,especially when there is a need for rapid onset therapeutic effects(Hanson, Venturelli & Fleckenstein, 2006). When dealing withchronic diseases, having a delay in the start of absorption of themedication does not have any clinical effect as long as the drug thathas been absorbed is not affected.
Foodand drugs can both increase and decrease the extent of having drugabsorption. The effects of food depend on both the pharmaceutics andphysiochemical characteristics of drugs. So as to achieve clinicalsignificance, there is the need of having pharmacodynamicscharacteristics of the medicine that the patient is taking. Forinstance medications that have a low saquinavir must always be takenon a full stomach just to allow the enhancement of the drugdissolution that in turn facilitates the absorption. On the samenote, it is important to note that the absorption rate increase bytwo if a patient takes saquinavir especially after taking a heavy andrich breakfast. It is these same effects that medicines have infact, other drugs cause serious side effects when mixed withmedications (Bloch, Maillet, Howell, & Winkler, 2007).
Mealsand drugs may have variable and in most cases might be unpredictableon how they with react with the drug that one is taking. However, byunderstanding the effects of clinical consequences of these effects,it is possible for heat professionals to provide advice on the bestway of ingesting medicines in regards to times and composition meals.The provision of timely as well as appropriate information on thepossible effects of meals and other drugs and the importance ofhaving proper timing are essential when it comes to takingmedications (DeBruyne, Pinna, Whitney, 2012). .
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choicesin clinical nutrition practice.Philadelphia: Lippincott Williams & Wilkins.
DeBruyne,L. K., Pinna, K., & Whitney, E. N. (2012). Nutritionand diet therapy.Belmont,
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Hanson,G., Venturelli, P. J., & Fleckenstein, A. E. (2006). Drugsand society.Sudbury,
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